Changes to exhaled nitric oxide in asthmatic children after drinking a caffeine-containing cola drink

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Caffeine decreases exhaled nitric oxide.

BACKGROUND Caffeine is known to inhibit phosphodiesterases, to mobilise intracellular calcium, and to act as an antagonist at adenosine receptors, all of which can potentially alter nitric oxide (NO) production. It was therefore hypothesised that caffeine may alter exhaled NO (eNO) levels. METHODS In a randomised, single blind, crossover manner, 12 normal subjects consumed either (1) coffee a...

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Factors attributable to the level of exhaled nitric oxide in asthmatic children

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ژورنال

عنوان ژورنال: Pediatric Pulmonology

سال: 2010

ISSN: 8755-6863

DOI: 10.1002/ppul.21313